Summary: The efficacy rate of 95 per cent claimed for Pfizer’s mRNA vaccine deconstructed by Dr Philip Altman as well as by the Canadian COVID Care Alliance (relative versus absolute risk reduction); excerpt and clip.


95 per cent efficacy’, they said.


Dr Philip Altman is an Australian with some 50 years of experience in the areas of clinical medical research and pharmaceutical drug regulatory affairs who recently released a report on the safety and efficacy profiles of the mRNA vaccines. I reproduced the table of contents of the report in a short blog article I published on this important compilation of the findings of an unbiased industry expert. Although I have not read Dr Altman’s report from the first page to the last, the following short paragraphs struck me as very important when I read the first third of the report on the very night I came across it. These paragraphs focus on the much touted rate of efficacy of 95% claimed for Pfizer’s mRNA vaccine. Well, the Australian veteran pharmacological expert Dr Philip Altman does a good job at deconstructing this claim. So please find below the excerpt from the Altman report where Dr Philip Altman does so, preceded by a similar deconstructive exercise in audio-visual format that was carried out roughly 10 months ago by the Canadian COVID Care Alliance: ‘relative versus absolute risk reduction (I came across the clip on 28th October 2021, a day after it had been uploaded on to Rumble).


[Click on the picture with the right button of your mouse, then on picture-in-picture’ in the menu and finally place your cursor on the picture at the bottom of the screen to display the ‘Play’ icon [i.e. the white arrow pointing towards the right] to start the clip, which will thus play in ‘picture-in-picture’ mode.

If it does not, click on https://sp.rmbl.ws/s8/2/f/V/Y/B/fVYBc.caa.mp4.






Sources:
https://www.canadiancovidcarealliance.org/media-resources/relative-vs-absolute-risk-reduction
https://rumble.com/vobcg5-relative-vs-absolute-risk-reduction.html



Excerpt from the Altman report, on pages 11 to 12:

[…]
5.3.   A good example of the popular misconceptions concerning the gene-based COVID-19 ‘vaccines’ is the claim of 95% efficacy which was repeated and unchallenged in the mainstream media and by health authorities in Australia and elsewhere.

5.4.   Approval of the gene-based COVID-19 ‘vaccines’ were [sic] based on single clinical trials from each company. These single trials were the sole basis for both the safety and efficacy claims. For example, in the case of the Pfizer gene-based ‘vaccine’ it was widely stated and generally accepted at the time that the clinical efficacy of the vaccine was determined in a large clinical trial of about 44,000 subjects and the efficacy was 95%.  

5.5.   Without an understanding of the design, conduct and reporting of clinical trials, the ordinary person might interpret this statement in a number of different ways.  For example, this “95%” efficacy might be interpreted to mean that vaccination provides a 95% chance of being protected from being infected following exposure from a person infected with SARS-CoV-2; or it might be interpreted to mean that vaccination reduces the risk of the average healthy person falling seriously ill and needing hospitalisation following SARS-CoV-2 infection; or it might be interpreted as showing the risk of death due to severe COVID-19 illness is reduced by 95%.

5.6.   Indeed, none of these interpretations are [sic] correct.  

5.7.   The claimed 95% efficacy was based upon only 170 subjects who contracted COVID- 19 during the trial which had a median follow up of two months post-second dose. The claimed clinical efficacy was not based upon 44,000 subjects. Of the 44,000 subjects enrolled and divided roughly equally between receiving active prophylactic vaccination or placebo, only 170 subjects tested positive for COVID-19 AND developed even mild COVID-19 symptoms (similar to the common cold) which was the criterion set for “clinical efficacy”; with eight testing positive in the vaccinated group AND displaying a COVID-19 symptom as mild as a sore throat, fever or cough, while 162 tested positive in the placebo group AND displayed a COVID-19 symptom as mild as a sore throat, fever or cough. This is where the 95% COVID “vaccine” efficacy claim originated and, based on this pivotal data, it should not be inferred that the Pfizer COVID-19 “vaccine was shown to be 95% effective in preventing serious COVID-19 disease, symptoms, hospitalisation or death” 23 .  
 
5.8.   The Pfizer trial (mentioned above) reported 99.07% of unvaccinated individuals did not develop symptoms of COVID-19 while 99.95% the vaccinated group did not report COVID-19 symptoms thus producing an absolute risk reduction of symptoms of 0.88%.
This statistic is a realistic measure of protection from COVID-19 (which may only present as mild symptoms) in an uninfected population over the trial surveillance period.    

5.9.   A subsequent Pfizer COMIRNATY gene-based COVID-19 ‘vaccine’ trial which was pivotal in the approval of this ‘vaccine’ for children 5-11 relied on the clinical symptoms of only 19 children (3 developed symptoms in the Comirnaty vaccine group and 16 in the placebo group) upon which to base its claimed a relative clinical efficacy of 90.7%. 24   Once again, the claimed clinical efficacy only referred to the chance of preventing the mild symptoms, similar to the common cold, in children who tested positive for COVID-19. The absolute vaccine clinical efficacy to prevent even mild symptoms among the 4500 trial participants can then be calculated to be under 1%.
 
5.10.  A similar approach was adopted by other manufacturers such as Moderna claiming similar “efficacy” which has not been understood by either the media or the lay public.

[Footnotes]
23  Australian Government – Therapeutic Goods Administration (25 January 2021) Australian Public Assessment Report for BNT162b2 (mRNA), Comirnaty, Pfizer Australia Pty Ltd – PM-2020-05461-1-2 Final
https://www.tga.gov.au/sites/default/files/auspar-bnt162b2-mrna-210125.pdf
 
24  Australian Government – Therapeutic Goods Administration (7 December 2021) Australian Public Assessment Report for Tozinameran (mRNA Covid-19 vaccine), Comirnaty, Pfizer Australia Pty Ltd– PM-2021-05012-1-2 https://www.tga.gov.au/sites/default/files/auspar-tozinameran-mrna-covid-19-vaccine-211207.pdf


The Altman report can be downloaded from
https://8630368.fs1.hubspotusercontent-na1.net/hubfs/8630368/AMPS/Altman%20Report%20Final%20Version%2011-8-22%20(1).pdf

1-9-2022
The Altman report, paragraphs 8.40 to 8.42 (infertility plus the toxic effects of the lipid nano particles)
https://paulzanotelli.ch/blog/coronavirus/mrna-adverse-events/impact-on-human-reproduction/the-altman-report-paragraphs-8.40-to-8.42.html

30-8-2022
Dr Philip Altman’s report on the mRNA vaccines
https://paulzanotelli.ch/blog/coronavirus/mrna-adverse-events/the-altman-report_11-8-2022.html


Lausanne, the above was published on the eighth day of the ninth month of the year two thousand and twenty-two.